The U.S. life sciences real estate market has reached an inflection point, creating new opportunities and challenges across the industry. JLL’s 2025 Life Sciences Real Estate Perspective and Cluster Analysis reveals a market environment increasingly favorable to tenants, with 61 million square feet of lab space available as demand patterns have shifted considerably. In addition to revealing the top life sciences ecosystems, the report discusses the key trends reshaping the industry, including global pharmaceutical companies pledging $475 billion year-to-date in U.S. manufacturing and R&D investments, the critical need for venture capital investment in the sector, artificial intelligence (AI) and a projected 18.7 million square feet of available space likely shifting to alternative uses by 2030.
“We’re witnessing a historic market correctio
